Germ Cell Transplantation in Fisheries: A Promising Step Toward Conservation
Surrogate broodstock technology based on germ cell transplantation provides a powerful
approach for conservation of aquatic genetic resources and enhancement of aquaculture
production at scale. In fish, germline stem cells or primordial germ cells from donor gonads or
embryos can be cryopreserved, transplanted into sterilized or germ cell-depleted recipients and
then reconstituted as functional gametes of donor origin under controlled conditions. The
strategy avoids technical limitations of oocyte cryopreservation, maternal inheritance of
mitochondria, and long generation intervals for large-bodied or late-maturing species.
Successful intra- and interspecific applications have been reported in commercially valuable
taxa like pufferfish and sturgeons and also in Indian major carps where cryopreserved
spermatogonia are revived in allogeneic hosts. The integration of surrogate broodstock systems
with genome editing and environmentally benign sterilisation tools such as thermal
manipulation further creates opportunities for secure cryopreservation, rapid propagation of
elite germplasm and safe restoration of endangered populations over coming decades.